Expert on hormonal regulation of cardiovascular and placental function
- Understanding mechanisms of vascular adaptations during pregnancy and how alterations in androgens, renin angiotensin system, etc lead to development of gestational hypertension and preeclampsia.
- Examine the mechanisms of nutrient transport across the placenta to fetus, and how this is perturbed during fetal growth restriction.
- Investigate the fetal and neonatal programming of sex differences in adult onset cardiovascular and metabolic disorders.
- Understand hypertension signaling mechanisms. How sex steroid hormones (androgens and estrogens) differentially regulate vascular smooth muscle and endothelial cell function in male vs females?