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Xinyu Zhao
Regulation of stem cells and development in brain health and diseases, including autism and fragile X syndrome.
Professor, neuroscience School of Medicine and Public Health Work: 608-263-9906 — Home and cell phones available upon request xinyu.zhao@wisc.edu Home page Twitter: @lab_zhao
Topics
- Study functions of RNA and RNA binding proteins in health and brain disorders, including autism, fragile X syndrome, Rett syndrome, and schizophrenia.
- Investigate epigenetic regulations and gene and environmental interactions in stem cells and development using gene editing, mouse genetics and human iPSCs
- Cell type specific and single cell analyses of stem cells and neurons using genomics, transcriptomics, proteomics, and Patch-seq.
- Determine how gene mutations leads to neuronal and behavioral changes in mouse models for human diseases.
Achievements
- Unveil how mutations of genes contribute to neural developmental disorders, including autism and fragile X syndrome affect brain development
- Uncover mitochondrial deficits in fragile X syndrome, a genetic form of autism.
- Mentoring undergraduate and graduate students, postdoctoral fellows, scientists, and junior faculty members