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Xinyu Zhao

Xinyu Zhao

Regulation of stem cells and development in brain health and diseases, including autism and fragile X syndrome.

Professor, neuroscience School of Medicine and Public Health Work: 608-263-9906 — Home and cell phones available upon request Home page Twitter: @lab_zhao


  • Study functions of RNA and RNA binding proteins in health and brain disorders, including autism, fragile X syndrome, Rett syndrome, and schizophrenia.
  • Investigate epigenetic regulations and gene and environmental interactions in stem cells and development using gene editing, mouse genetics and human iPSCs
  • Cell type specific and single cell analyses of stem cells and neurons using genomics, transcriptomics, proteomics, and Patch-seq.
  • Determine how gene mutations leads to neuronal and behavioral changes in mouse models for human diseases.


  • Unveil how mutations of genes contribute to neural developmental disorders, including autism and fragile X syndrome affect brain development
  • Uncover mitochondrial deficits in fragile X syndrome, a genetic form of autism.
  • Mentoring undergraduate and graduate students, postdoctoral fellows, scientists, and junior faculty members